RAD1 and HUS1B

Data Source:
HPRD (in vivo, two hybrid)

		RAD1	HUS1B
Description		RAD1 checkpoint DNA exonuclease	HUS1 checkpoint clamp component B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Checkpoint Clamp Complex Intracellular Membrane-bounded Organelle	Nucleolus Checkpoint Clamp Complex Site Of Double-strand Break
	Molecular Function	Damaged DNA Binding Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Substantia Nigra Development Meiotic Recombination Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Nucleotide-excision Repair Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	Aging ( 22773346) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: COPS5 CSNK2A1 CSNK2A2 DNAJC7 FEN1 HUS1 HUS1B MAP1LC3B MSH2 MSH3 MSH6 NEIL1 OGG1 POLB PRKN RAD17 RAD9B RHNO1 RPA1 RPA2 SIRT6 TDG TOPBP1 WRN	4 interacting genes: HUS1 RAD1 RAD9A RAD9B
Entrez ID		5810	135458
HPRD ID		04400	13722
Ensembl ID		ENSG00000113456	ENSG00000188996
Uniprot IDs		A0A024R045 O60671	Q8NHY5
PDB IDs		3A1J 3G65 3GGR 6J8Y
Enriched GO Terms of Interacting Partners?
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