PTPRH and DOK1

Data Source:
HPRD (in vivo)

		PTPRH	DOK1
Description		protein tyrosine phosphatase receptor type H	docking protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane Apical Plasma Membrane Microvillus Membrane	Nucleus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Apoptotic Process Peptidyl-tyrosine Dephosphorylation	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Axon Guidance Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Pathways			PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RET signaling
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic lupus erythematosus ( 28714469)	Height ( 31562340)
Interacting Genes		15 interacting genes: BCAR1 CRK DHPS DOK1 EGFR ERBB3 ERBB4 GHR KRTAP10-3 KRTAP10-8 LCK MAPK1 MLH1 PTK2 PXN	41 interacting genes: ABL1 ABL2 BCR CRK CRKL CSK DOK3 ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC TLN1 VAV1 YES1
Entrez ID		5794	1796
HPRD ID		03942	04228
Ensembl ID		ENSG00000080031	ENSG00000115325
Uniprot IDs		Q9HD43	B3KP83 B4DJN1 Q14CB2 Q2TA81 Q99704
PDB IDs			2V76
Enriched GO Terms of Interacting Partners?
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