DOK1 and DOK3

Data Source:
BioGRID (two hybrid)

		DOK1	DOK3
Description		docking protein 1	docking protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Perinuclear Region Of Cytoplasm	Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Axon Guidance Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway	Neutrophil Degranulation
Pathways		PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 RET signaling	Neutrophil degranulation
Drugs
Diseases
GWAS		Height ( 31562340)	Coronary artery disease ( 29212778) Inflammatory bowel disease ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		41 interacting genes: ABL1 ABL2 BCR CRK CRKL CSK DOK3 ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC TLN1 VAV1 YES1	31 interacting genes: A1CF ABL1 ANKS1A APPL1 APPL2 COX5B CRK CSK DOK1 DOK2 DOK5 DTX2 FYN GCM2 HOXA1 INPP5D LCK LYN MDFI PLEKHA3 PPIH PRKAB2 RBPMS RET RIN3 SHC3 SHE SPAG8 STAT3 TNS2 TRAF1
Entrez ID		1796	79930
HPRD ID		04228	16834
Ensembl ID		ENSG00000115325	ENSG00000146094
Uniprot IDs		B3KP83 B4DJN1 Q14CB2 Q2TA81 Q99704	A0A024R7M5 A0A6M4C8X9 D6RAM3 Q7L591
PDB IDs		2V76
Enriched GO Terms of Interacting Partners?
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