PTPN9 and RTN3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTPN9	RTN3
Description		protein tyrosine phosphatase non-receptor type 9	reticulon 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Neuron Projection Terminus	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane	Apoptotic Process Viral Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation
Pathways		Interleukin-37 signaling	Synaptic adhesion-like molecules
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)
Interacting Genes		46 interacting genes: AGTRAP AQP6 ARL13B ARL6IP1 ATP5PF BSND CCR2 CDR1 CERS4 CMTM4 CMTM5 COQ3 CPLX4 CREB3 CREB3L1 DERL2 EBP FAM114A2 FKBP7 GET1 GHR GJB1 GORAB HSD17B11 HSD17B13 LIME1 LMNA MAL2 NSF PBX3 PEX12 PLIN3 REEP6 RTN3 SCAMP1 SLC16A13 SLC30A8 SLC7A1 SPAG4 STX6 SYP TMCO2 TMEM80 TMEM86B TMX2 YIF1A	30 interacting genes: AGTR1 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391
Entrez ID		5780	10313
HPRD ID		02864	18516
Ensembl ID		ENSG00000169410	ENSG00000133318
Uniprot IDs		P43378 Q6IQ43	A0A024R5C4 O95197
PDB IDs		2PA5 4GE2 4GE5 4GE6 4ICZ 6KZQ 6L03	7BRU
Enriched GO Terms of Interacting Partners?
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