PTGER3 and CDA

Data Source:
BioGRID (two hybrid)

		PTGER3	CDA
Description		prostaglandin E receptor 3	cytidine deaminase
Image
GO Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Prostaglandin E Receptor Activity	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process
Pathways		Prostanoid ligand receptors G alpha (i) signalling events	Neutrophil degranulation Pyrimidine salvage
Drugs		Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost Castor oil	1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)	Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598
Entrez ID		5733	978
HPRD ID		08906	11744
Ensembl ID		ENSG00000050628	ENSG00000158825
Uniprot IDs		O00325 P43115	P32320
PDB IDs		6AK3 6M9T	1MQ0
Enriched GO Terms of Interacting Partners?
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