PTGER3 and PTGER1

Data Source:
HPRD (in vitro)

		PTGER3	PTGER1
Description		prostaglandin E receptor 3	prostaglandin E receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Prostaglandin E Receptor Activity	Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipopolysaccharide Negative Regulation Of Gastric Emptying
Pathways		Prostanoid ligand receptors G alpha (i) signalling events	Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost Castor oil	Bupivacaine Carboprost tromethamine Alprostadil Bimatoprost Dinoprostone Misoprostol Iloprost Limaprost
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		5733	5731
HPRD ID		08906	08903
Ensembl ID		ENSG00000050628	ENSG00000160951
Uniprot IDs		O00325 P43115	P34995
PDB IDs		6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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