PTGER3 and KRT38

Data Source:
BioGRID (two hybrid)

		PTGER3	KRT38
Description		prostaglandin E receptor 3	keratin 38
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Prostaglandin E Receptor Activity	Structural Molecule Activity Protein Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion	Keratinization Cornification
Pathways		Prostanoid ligand receptors G alpha (i) signalling events	Keratinization Formation of the cornified envelope
Drugs		Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost Castor oil
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	72 interacting genes: - ABI3 AMOTL2 ANKRD36BP1 BEX2 BRME1 C1orf216 CCDC120 CCDC146 CD300A CEP57L1 DMRT3 DTNB FAM110A FAM90A1 GLRX3 GNG10 GNG13 HAUS1 HDAC4 HGS HMG20B HOXA1 HSF4 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LHX4 LMO3 LMO4 MAGEB4 MAPKBP1 PIK3R2 PIN1 POU4F2 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 SMARCD1 TBC1D21 TRIML2 TXLNA TXLNB TXNDC5 USHBP1 UTP23 ZFYVE21 ZNF20 ZNF417 ZNF587
Entrez ID		5733	8687
HPRD ID		08906	05176
Ensembl ID		ENSG00000050628	ENSG00000171360
Uniprot IDs		O00325 P43115	O76015
PDB IDs		6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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