PTGDS and HK3

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PTGDS	HK3
Description		prostaglandin D2 synthase	hexokinase 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Mitochondrion Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding Small Molecule Binding	Glucokinase Activity Hexokinase Activity Protein Binding ATP Binding Glucose Binding Fructokinase Activity Mannokinase Activity
	Biological Process	Prostaglandin Biosynthetic Process Cyclooxygenase Pathway Mast Cell Degranulation Regulation Of Circadian Sleep/wake Cycle, Sleep	Cellular Glucose Homeostasis Fructose 6-phosphate Metabolic Process Glycolytic Process Neutrophil Degranulation Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Canonical Glycolysis
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Transcriptional regulation of testis differentiation	Neutrophil degranulation Glycolysis
Drugs		Vitamin A
Diseases
GWAS		Beta-trace protein levels ( 23328707) Blood protein levels ( 29875488) Corneal structure ( 23291589)	Uterine fibroids ( 30194396) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: ADRB2 AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 CARD10 CYSRT1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 KRTAP12-3 MLH1 PTGER1 PTGER2 PTGFR SHBG UBQLN2	10 interacting genes: ATF4 GRN HPGDS IGFBP4 LEP MEOX2 MITF PPP2CB PTGDS ZBTB17
Entrez ID		5730	3101
HPRD ID		08904	00806
Ensembl ID		ENSG00000107317	ENSG00000160883
Uniprot IDs		A0A024R8G3 P41222	A0A024R7R1 P52790
PDB IDs		2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9	3HM8
Enriched GO Terms of Interacting Partners?
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