THAP11 and SRSF11

Data Source:
BioGRID (two hybrid)

		THAP11	SRSF11
Description		THAP domain containing 11	serine and arginine rich splicing factor 11
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		20 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	30 interacting genes: ARL6IP4 ATP5F1D CDK6 CSNK2A1 DACH1 DDOST DUSP29 ETS1 GATC HNRNPLL HYI LNX2 MDM2 MEOX2 PAX6 PIN1 PUF60 RBM39 RNPS1 SDCBP SREK1 SRPK2 SRRM4 SRSF1 SRSF2 TANK THAP11 TOP1 U2AF2 ZNF385C
Entrez ID		57215	9295
HPRD ID		11629	03599
Ensembl ID		ENSG00000168286	ENSG00000116754
Uniprot IDs		Q96EK4	Q05519
PDB IDs		2LAU 5AJS
Enriched GO Terms of Interacting Partners?
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