THAP11 and PFDN6

Data Source:
BioGRID (two hybrid)

		THAP11	PFDN6
Description		THAP domain containing 11	prefoldin subunit 6
Image
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Cytoplasm Prefoldin Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Protein Folding Chaperone-mediated Protein Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		20 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	12 interacting genes: AIMP2 B4GALT2 CCHCR1 CEBPG FBXO2 KANK2 KIFC3 MAGEB4 MBD3 PFDN5 RPRD1B THAP11
Entrez ID		57215	10471
HPRD ID		11629	16135
Ensembl ID		ENSG00000168286	ENSG00000204220
Uniprot IDs		Q96EK4	O15212 Q5STK2
PDB IDs		2LAU 5AJS	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?