GOPC and PPP1R18

Data Source:
BioGRID (two hybrid)

		GOPC	PPP1R18
Description		golgi associated PDZ and coiled-coil motif containing	protein phosphatase 1 regulatory subunit 18
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding Ion Channel Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface
Pathways		RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		70 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 ATG9A BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		57120	170954
HPRD ID		06024	11172
Ensembl ID		ENSG00000047932	ENSG00000146112
Uniprot IDs		Q9HD26	A0A024RCJ8 Q6NYC8
PDB IDs		2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6XNJ
Enriched GO Terms of Interacting Partners?
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