GOPC and LCLAT1

Data Source:
BioGRID (two hybrid)

		GOPC	LCLAT1
Description		golgi associated PDZ and coiled-coil motif containing	lysocardiolipin acyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding Ion Channel Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity, Transferring Acyl Groups
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Negative Regulation Of Protein Localization To Cell Surface	Phosphatidic Acid Biosynthetic Process Multicellular Organism Development CDP-diacylglycerol Biosynthetic Process Cardiolipin Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling
Pathways		RHO GTPases regulate CFTR trafficking	Acyl chain remodeling of CL Synthesis of PA
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)	Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828)
Interacting Genes		70 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 ATG9A BATF BECN1 C17orf67 CCDC102B CCDC198 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GEM GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 OSBP2 PARK7 PID1 PPP1R18 PWWP3A RALGAPB RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SNX31 SPATA8 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZDHHC1 ZNF564 ZNF581 ZNF587 ZNF835 ZSCAN1	3 interacting genes: GOPC LNX1 PICK1
Entrez ID		57120	253558
HPRD ID		06024	17458
Ensembl ID		ENSG00000047932	ENSG00000172954
Uniprot IDs		Q9HD26	B4DM26 B4DYR5 Q6UWP7
PDB IDs		2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7 6XNJ
Enriched GO Terms of Interacting Partners?
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