ODC1 and SSR1

Data Source:
BioGRID (two hybrid)

		ODC1	SSR1
Description		ornithine decarboxylase 1	signal sequence receptor subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Response To Virus Putrescine Biosynthetic Process From Ornithine Regulation Of Protein Catabolic Process	Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Population Proliferation IRE1-mediated Unfolded Protein Response
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
Drugs		Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Ewing sarcoma ( 30093639) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 24509480 32499647 30718926 28869590)
Interacting Genes		18 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 OAZ3 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	8 interacting genes: DKC1 EEF1A1 HSPA13 NUP54 ODC1 PTN SERPINF2 UTP14A
Entrez ID		4953	6745
HPRD ID		01324	02924
Ensembl ID		ENSG00000115758	ENSG00000124783
Uniprot IDs		B4DXF8 P11926	C9JBX5 P43307
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA
Enriched GO Terms of Interacting Partners?
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