OTUD7B and CDIP1

Data Source:
BioGRID (two hybrid)

		OTUD7B	CDIP1
Description		OTU deubiquitinase 7B	cell death inducing p53 target 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	DNA Binding Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Zinc Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Lys48-specific Deubiquitinase Activity	Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Adaptive Immune Response Mucosal Immune Response Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Interleukin-8 Production Protein K11-linked Deubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Localization To Nucleus	Apoptotic Process Tumor Necrosis Factor-mediated Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways		TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ovarian tumor domain proteases
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Breast cancer ( 29059683) Heel bone mineral density ( 30598549) Height ( 25282103) Obesity-related traits ( 23251661) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Triglyceride levels ( 32154731)	Eosinophil percentage of white cells ( 32888494) Schizophrenia ( 28991256)
Interacting Genes		18 interacting genes: AURKA CCNB1 CDC20 CDIP1 DAZAP2 EPM2AIP1 FZR1 HSFY1 HSFY2 OTULIN PPP1R32 PSMB1 SOX2 SPART TRAF6 UBC UBE2S ZDHHC17	14 interacting genes: ATXN1 CCR2 DCUN1D1 DESI1 EPN2 LAT OTUB2 OTUD7B TNIP1 TOLLIP UBB UBC UBQLN1 UBQLN2
Entrez ID		56957	29965
HPRD ID		10313	12676
Ensembl ID		ENSG00000264522	ENSG00000089486
Uniprot IDs		Q6GQQ9	Q9H305
PDB IDs		5LRU 5LRV 5LRW
Enriched GO Terms of Interacting Partners?
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