OTUD7B and SOX2

OTUD7B

SOX2

Description OTU deubiquitinase 7B SRY-box transcription factor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Breast cancer ( 29059683)
  • Heel bone mineral density ( 30598549)
  • Height ( 25282103)
  • Obesity-related traits ( 23251661)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Triglyceride levels ( 32154731)
Interacting Genes 18 interacting genes: AURKA CCNB1 CDC20 CDIP1 DAZAP2 EPM2AIP1 FZR1 HSFY1 HSFY2 OTULIN PPP1R32 PSMB1 SOX2 SPART TRAF6 UBC UBE2S ZDHHC17 17 interacting genes: AKT1 ALX4 CASP8 CDX1 COP1 FZR1 L3MBTL3 MAPK3 NR5A1 OTUD7B POU2F1 POU5F1 SETD7 SUMO1 UBE2D3 UBR5 XPO1
Entrez ID 56957 6657
HPRD ID 10313 08921
Ensembl ID ENSG00000264522 ENSG00000181449
Uniprot IDs Q6GQQ9 A0A0U3FYV6 P48431
PDB IDs 5LRU 5LRV 5LRW 1O4X 2LE4 6T7B 6T90 6WX7 6WX8 6WX9 6YOV
Enriched GO Terms of Interacting Partners?
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