CDIP1 and TOLLIP

Data Source:
BioGRID (two hybrid)

		CDIP1	TOLLIP
Description		cell death inducing p53 target 1	toll interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane	Extracellular Region Cytoplasm Cytosol Nuclear Body Protein-containing Complex Azurophil Granule Lumen Specific Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Metal Ion Binding	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding
	Biological Process	Apoptotic Process Tumor Necrosis Factor-mediated Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator	Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Protein Localization To Endosome Neutrophil Degranulation Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway
Pathways			Neutrophil degranulation Interleukin-1 signaling
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Schizophrenia ( 28991256)	Gout ( 32238385) Idiopathic pulmonary fibrosis ( 24429156)
Interacting Genes		14 interacting genes: ATXN1 CCR2 DCUN1D1 DESI1 EPN2 LAT OTUB2 OTUD7B TNIP1 TOLLIP UBB UBC UBQLN1 UBQLN2	78 interacting genes: ACTN2 ARRDC3 ATXN1 BHLHE40 C19orf54 CDIP1 CHD6 CPSF6 CSN1S1 CSN2 CSTF1 DAB1 DAZAP2 DCDC2 DDIT4L DZIP3 EIF2AK2 FAM166B FAM168A FTH1 GGA1 GGA2 GGA3 GUCD1 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 KRTAP13-3 KRTAP15-1 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP7-1 LDB1 MEDAG MSS51 MSX2 MVP N4BP2 NRF1 NTAQ1 ODAM PEG10 PHAF1 PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB1 RBFOX1 RBFOX2 RBPMS RHOXF2 SEPTIN1 SETDB1 SIAH1 STN1 TBX3 TENT5A TLR2 TLR4 TOM1 TOM1L1 TOM1L2 TTC9C UBC USP54 WBP2 WRNIP1 XRN2 ZBTB16 ZHX1 ZMYND19 ZRANB1
Entrez ID		29965	54472
HPRD ID		12676	05887
Ensembl ID		ENSG00000089486	ENSG00000078902
Uniprot IDs		Q9H305	B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2
PDB IDs			1WGL 2N31
Enriched GO Terms of Interacting Partners?
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