SAR1A and UPK1B

Data Source:
BioGRID (two hybrid)

		SAR1A	UPK1B
Description		secretion associated Ras related GTPase 1A	uroplakin 1B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Structural Molecule Activity Protein Binding
	Biological Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum COPII-coated Vesicle Cargo Loading	Response To Bacterium Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
Interacting Genes		69 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 C14orf180 C3orf52 CD53 CD81 CES1 CLDN19 CLDND2 CLEC7A CMTM5 COL4A5 CTSA CXCL16 EMP3 ERG28 FAM3C GJB2 GOLT1B GRM2 GYPA HMOX2 JAGN1 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM ORMDL1 PLLP PLN PLP2 RHOT2 RMDN2 SEC22A SERP1 SLC35A1 SMIM1 SNAP47 STX7 STX8 TMEM107 TMEM109 TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5	53 interacting genes: BCL2L13 BEST2 BNIP2 CD53 CD69 CERS4 CLDN7 DAGLA EDAR FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A2 SLC16A2 SLC35C2 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM262 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1
Entrez ID		56681	7348
HPRD ID		07608	03853
Ensembl ID		ENSG00000079332	ENSG00000114638
Uniprot IDs		Q5SQT9 Q9NR31	O75841
PDB IDs		2GAO
Enriched GO Terms of Interacting Partners?
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