UPK1B and GPR161

Data Source:
BioGRID (two hybrid)

		UPK1B	GPR161
Description		uroplakin 1B	G protein-coupled receptor 161
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque	Cilium Integral Component Of Membrane Endocytic Vesicle Membrane Recycling Endosome Ciliary Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Response To Bacterium Epithelial Cell Differentiation	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways			Hedgehog 'off' state Hedgehog 'on' state
Drugs
Diseases
GWAS		Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)	Red cell distribution width ( 27863252)
Interacting Genes		53 interacting genes: BCL2L13 BEST2 BNIP2 CD53 CD69 CERS4 CLDN7 DAGLA EDAR FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A2 SLC16A2 SLC35C2 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM262 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1	7 interacting genes: CCR2 CLDN19 COMT EFNA5 GPR35 SLC30A2 UPK1B
Entrez ID		7348	23432
HPRD ID		03853	17070
Ensembl ID		ENSG00000114638	ENSG00000143147
Uniprot IDs		O75841	A0A0A0MQW8 Q8N6U8
PDB IDs
Enriched GO Terms of Interacting Partners?
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