SAR1A and RHOT2

Data Source:
BioGRID (two hybrid)

		SAR1A	RHOT2
Description		secretion associated Ras related GTPase 1A	ras homolog family member T2
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GO Annotations	Cellular Component	Golgi Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Mitochondrion Cytosol Plasma Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding
	Biological Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum COPII-coated Vesicle Cargo Loading	Mitochondrion Organization Regulation Of Mitochondrion Organization Cellular Homeostasis Mitochondrion Transport Along Microtubule Regulation Of Small GTPase Mediated Signal Transduction Mitochondrial Outer Membrane Permeabilization
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS			Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red blood cell traits ( 23446634)
Interacting Genes		69 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 C14orf180 C3orf52 CD53 CD81 CES1 CLDN19 CLDND2 CLEC7A CMTM5 COL4A5 CTSA CXCL16 EMP3 ERG28 FAM3C GJB2 GOLT1B GRM2 GYPA HMOX2 JAGN1 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM ORMDL1 PLLP PLN PLP2 RHOT2 RMDN2 SEC22A SERP1 SLC35A1 SMIM1 SNAP47 STX7 STX8 TMEM107 TMEM109 TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5	5 interacting genes: PRKN SAR1A TMEM14B TMEM86B ZFYVE9
Entrez ID		56681	89941
HPRD ID		07608	15248
Ensembl ID		ENSG00000079332	ENSG00000140983
Uniprot IDs		Q5SQT9 Q9NR31	Q8IXI1
PDB IDs		2GAO	5KUT
Enriched GO Terms of Interacting Partners?
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