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VPS11 and RDX
Data Source:
BioGRID
(pull down)
VPS11
RDX
Description
VPS11 core subunit of CORVET and HOPS complexes
radixin
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Lysosome
Lysosomal Membrane
Endosome
Early Endosome
Late Endosome
Autophagosome
Clathrin-coated Vesicle
Endocytic Vesicle
HOPS Complex
Late Endosome Membrane
Extracellular Space
Plasma Membrane
Microvillus
Adherens Junction
Focal Adhesion
Apical Plasma Membrane
Lamellipodium
Filopodium
T-tubule
Midbody
Cortical Actin Cytoskeleton
Cleavage Furrow
Cell Tip
Extracellular Exosome
Cell Periphery
Molecular Function
Nucleotide Binding
Protein Binding
Protein Domain Specific Binding
Syntaxin Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
RNA Binding
Actin Binding
Protein Binding
Cadherin Binding
Protein Kinase A Binding
ATPase Binding
Biological Process
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Autophagy
Endosome Organization
Vacuole Organization
Endosome To Lysosome Transport
Protein Ubiquitination
Regulation Of Protein Stability
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Endosomal Vesicle Fusion
Regulation Of SNARE Complex Assembly
Regulation Of Organelle Assembly
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Early Endosome To Late Endosome Transport
Regulation Of Cell Shape
Regulation Of Cell Size
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Positive Regulation Of Cell Migration
Regulation Of Actin Filament Bundle Assembly
Regulation Of Rap Protein Signal Transduction
Negative Regulation Of Homotypic Cell-cell Adhesion
Negative Regulation Of GTPase Activity
Cellular Response To Platelet-derived Growth Factor Stimulus
Regulation Of GTPase Activity
Apical Protein Localization
Establishment Of Protein Localization
Negative Regulation Of Cell Size
Barbed-end Actin Filament Capping
Establishment Of Endothelial Barrier
Protein Localization To Plasma Membrane
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Ruffle Assembly
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Organelle Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Adherens Junction Organization
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Recycling pathway of L1
Recycling pathway of L1
Drugs
1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS
Adult body size (
32376654
)
Body mass index (
29273807
)
Coronary artery disease (
29212778
33020668
)
HDL cholesterol levels (
32203549
)
Plateletcrit (
32888494
)
Cognitive function (
24684796
)
Coronary artery disease (
32469254
)
Multiple sclerosis (
31604244
)
Interacting Genes
33 interacting genes:
BCAR1
BMI1
ECPAS
EZR
GGA3
KDM1A
KRTAP10-3
KRTAP10-8
LRSAM1
LSM1
MARK3
MON1B
MSN
RAB7A
RDX
RILP
RNF181
STX1A
STX6
STX7
STX8
TFAP2B
TRIM32
TSG101
UBE2D2
UBE2L3
UBE2U
UVRAG
VPS16
VPS18
VPS33A
VPS39
VPS45
20 interacting genes:
ABCC2
ARHGDIA
C1QTNF9
CALM1
CPNE1
CPNE2
CPNE4
DRD3
EZR
GNA13
ICAM2
ITGB2
L1CAM
LINC01554
PSME3
ROCK1
SLC9A3R1
SLC9A3R2
TSC1
VPS11
Entrez ID
55823
5962
HPRD ID
12258
01534
Ensembl ID
ENSG00000160695
ENSG00000137710
Uniprot IDs
A0A087WXL6
B7Z879
Q9H270
B0YJ88
P35241
Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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