AGK and SNX4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		AGK	SNX4
Description		acylglycerol kinase	sorting nexin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex Intracellular Membrane-bounded Organelle	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Lipid Kinase Activity Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding D-erythro-sphingosine Kinase Activity Acylglycerol Kinase Activity Dihydroceramide Kinase Activity	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Sphingolipid Metabolic Process Phosphorylation Protein Insertion Into Mitochondrial Inner Membrane Glycerophospholipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Lipid Phosphorylation	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		Glycerophospholipid biosynthesis Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Mood disorder and prion disease ( 25897833)	Adult body size ( 32376654) Estimated glomerular filtration rate in non-diabetics ( 31451708) Urate levels ( 31578528)
Interacting Genes		3 interacting genes: HCK PDLIM1 SNX4	18 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 DGAT2L6 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SH3GLB1 SNX2 SNX6 SNX7 SUPT5H
Entrez ID		55750	8723
HPRD ID		08554	09334
Ensembl ID		ENSG00000006530	ENSG00000114520
Uniprot IDs		A4D1U5 Q53H12	O95219
PDB IDs		7CGP
Enriched GO Terms of Interacting Partners?
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