AGK and PDLIM1

Data Source:
HPRD (two hybrid)

		AGK	PDLIM1
Description		acylglycerol kinase	PDZ and LIM domain 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex Intracellular Membrane-bounded Organelle	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin
	Molecular Function	Lipid Kinase Activity Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding D-erythro-sphingosine Kinase Activity Acylglycerol Kinase Activity Dihydroceramide Kinase Activity	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Sphingolipid Metabolic Process Phosphorylation Protein Insertion Into Mitochondrial Inner Membrane Glycerophospholipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Lipid Phosphorylation	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion
Pathways		Glycerophospholipid biosynthesis Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Mood disorder and prion disease ( 25897833)	Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: HCK PDLIM1 SNX4	14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		55750	9124
HPRD ID		08554	09326
Ensembl ID		ENSG00000006530	ENSG00000107438
Uniprot IDs		A4D1U5 Q53H12	O00151 V9HW92
PDB IDs		7CGP	1X62 2PKT
Enriched GO Terms of Interacting Partners?
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