PNRC2 and SPAG9

Data Source:
BioGRID (two hybrid)

		PNRC2	SPAG9
Description		proline rich nuclear receptor coactivator 2	sperm associated antigen 9
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Golgi Apparatus Cytosol	Acrosomal Vesicle Cytoplasm Lysosomal Membrane Cytosol Centriolar Satellite Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	MAP-kinase Scaffold Activity Protein Binding JUN Kinase Binding Kinesin Binding Signaling Receptor Complex Adaptor Activity Identical Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-independent Decapping Of Nuclear-transcribed MRNA	Negative Regulation Of Protein Phosphorylation Activation Of JUN Kinase Activity Vesicle-mediated Transport Positive Regulation Of Cell Migration Lysosome Localization Retrograde Transport, Endosome To Golgi Negative Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Dendrite Extension
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Myogenesis Myogenesis
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Body fat mass ( 28552196) Conjunctival UV autofluorescence (CUVAF) ( 25590795) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: APP AR BANP DCP1A ESR1 ESR2 ESRRA ESRRG FBXO7 GALK1 GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SPAG9 XRCC6 ZBTB16 ZBTB48	12 interacting genes: ARF6 KLC1 MAP1LC3B MAP2K4 MAP3K3 MAPK14 MAPK8 MAX MYC NFKB1 PNRC2 TP53BP1
Entrez ID		55629	9043
HPRD ID		17871	10398
Ensembl ID		ENSG00000189266	ENSG00000008294
Uniprot IDs		Q9NPJ4	O60271 Q5JB53
PDB IDs		4B6H 5KQ1 5KQ4	2W83
Enriched GO Terms of Interacting Partners?
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