LRRC59 and SGO1

Data Source:
HPRD (in vivo)

		LRRC59	SGO1
Description		leucine rich repeat containing 59	shugoshin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondrial Nucleoid	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Chromosome, Centromeric Region Spindle Pole Nucleoplasm Centrosome Cytosol
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Protein Binding Kinase Binding
	Biological Process	Signal Transduction Positive Regulation Of Ras Protein Signal Transduction	Mitotic Sister Chromatid Segregation Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Centriole-centriole Cohesion Meiotic Chromosome Segregation Homologous Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Mitotic Sister Chromatid Cohesion, Centromeric
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		20 interacting genes: AGTRAP APP AQP1 CMTM3 CMTM5 CNIH1 CSNK2A1 EBP EDDM3B MTNR1A NDRG4 PLPP4 SGO1 SNORC TMBIM6 TMEM222 TMEM60 TMEM97 TRAM1L1 TSPO2	20 interacting genes: CDCA8 LRRC59 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET XRCC5 XRCC6
Entrez ID		55379	151648
HPRD ID		15181	12377
Ensembl ID		ENSG00000108829	ENSG00000129810
Uniprot IDs		Q96AG4	A0A024R2J4 B5BUA4 Q5FBB7
PDB IDs			3FGA 3Q6S 4A0I
Enriched GO Terms of Interacting Partners?
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