SGO1 and LRRC59

Data Source:
HPRD (in vivo)

		SGO1	LRRC59
Description		shugoshin 1	leucine rich repeat containing 59
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Chromosome, Centromeric Region Spindle Pole Nucleoplasm Centrosome Cytosol	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondrial Nucleoid
	Molecular Function	Protein Binding Kinase Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	Mitotic Sister Chromatid Segregation Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Centriole-centriole Cohesion Meiotic Chromosome Segregation Homologous Chromosome Segregation Meiotic Sister Chromatid Cohesion Cell Division Mitotic Sister Chromatid Cohesion, Centromeric	Signal Transduction Positive Regulation Of Ras Protein Signal Transduction
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes		20 interacting genes: CDCA8 LRRC59 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKDC RPL10A RPL28 RPL7 RPL7A RPLP1 SET XRCC5 XRCC6	20 interacting genes: AGTRAP APP AQP1 CMTM3 CMTM5 CNIH1 CSNK2A1 EBP EDDM3B MTNR1A NDRG4 PLPP4 SGO1 SNORC TMBIM6 TMEM222 TMEM60 TMEM97 TRAM1L1 TSPO2
Entrez ID		151648	55379
HPRD ID		12377	15181
Ensembl ID		ENSG00000129810	ENSG00000108829
Uniprot IDs		A0A024R2J4 B5BUA4 Q5FBB7	Q96AG4
PDB IDs		3FGA 3Q6S 4A0I
Enriched GO Terms of Interacting Partners?
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