PEF1 and KRTAP15-1

Data Source:
BioGRID (two hybrid)

		PEF1	KRTAP15-1
Description		penta-EF-hand domain containing 1	keratin associated protein 15-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Cytosol Intermediate Filament
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Keratinization
Pathways			Keratinization
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		40 interacting genes: AKAP8L ALG2 ANKRD10 BAG4 BPIFA1 C11orf1 CALCOCO2 CEP55 CTAG1A CTAG1B CUL3 DAZAP2 DMRTB1 EIF4G1 EWSR1 FAM168A FOXR2 HEMK1 HGS HYDIN INCA1 KLHL12 KRTAP12-1 KRTAP15-1 KRTAP19-1 MED25 METTL15 NR0B2 PDCD6 SEC24A SEC31A SMUG1 SOHLH1 SPAG8 SPG21 STH TFG VPS37C WWOX ZIC1	71 interacting genes: ACY3 ANKHD1 ARID5A ASB13 ATN1 C10orf55 CAMK2A CCDC24 CERCAM CYSRT1 DTX2 FCHO1 FOXD2 GEMIN4 GRN HOXA1 HR INCA1 INTS11 ITGB4 KPRP KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP6-2 KRTAP9-2 MGAT5B NEU4 NHLRC4 NOXA1 PATZ1 PEF1 PITX2 PLSCR3 POU1F1 POU2AF1 PRR13 PSMB1 RBPMS RHOXF2 RIN1 RNF208 SLC15A2 SMUG1 SOX14 SPAG8 TEKT3 TEKT5 TFAP2D TLE3 TOLLIP UBAP2 UFSP1 VAC14 VGLL3 VPS37C VWCE WDR25 YPEL3 ZBTB32 ZIC1
Entrez ID		553115	254950
HPRD ID		10143	11204
Ensembl ID		ENSG00000162517	ENSG00000186970
Uniprot IDs		A0A384MQX5 Q9UBV8	Q3LI76
PDB IDs
Enriched GO Terms of Interacting Partners?
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