KRTAP15-1 and ITGB4

Data Source:
BioGRID (two hybrid)

		KRTAP15-1	ITGB4
Description		keratin associated protein 15-1	integrin subunit beta 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Basement Membrane Nucleolus Plasma Membrane Focal Adhesion Integrin Complex Basal Plasma Membrane Cell Surface Cell Junction Hemidesmosome Cell Leading Edge Nuclear Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding	G Protein-coupled Receptor Binding Integrin Binding Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding
	Biological Process	Keratinization	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Peripheral Nervous System Myelin Formation Cell Adhesion Mediated By Integrin Nail Development Skin Morphogenesis Filopodium Assembly Mesodermal Cell Differentiation Cell Motility Trophoblast Cell Migration
Pathways		Keratinization	Assembly of collagen fibrils and other multimeric structures Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs			R1295
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS
Interacting Genes		71 interacting genes: ACY3 ANKHD1 ARID5A ASB13 ATN1 C10orf55 CAMK2A CCDC24 CERCAM CYSRT1 DTX2 FCHO1 FOXD2 GEMIN4 GRN HOXA1 HR INCA1 INTS11 ITGB4 KPRP KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP6-2 KRTAP9-2 MGAT5B NEU4 NHLRC4 NOXA1 PATZ1 PEF1 PITX2 PLSCR3 POU1F1 POU2AF1 PRR13 PSMB1 RBPMS RHOXF2 RIN1 RNF208 SLC15A2 SMUG1 SOX14 SPAG8 TEKT3 TEKT5 TFAP2D TLE3 TOLLIP UBAP2 UFSP1 VAC14 VGLL3 VPS37C VWCE WDR25 YPEL3 ZBTB32 ZIC1	59 interacting genes: ADAMTSL4 ALOX12 APPBP2 ATXN1 CLCA1 CLCA2 COL17A1 CYSRT1 DST ECM1 EIF6 ERBB2 ERBIN FYN GRB2 HOXA1 ITGA6 KPRP KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP4-2 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 MDFI MET MID2 MTUS2 MYF5 NBPF19 NOTCH2NLA PLEC PLSCR4 POU2AF1 PRKCA PRKCD PTK2 SDC2 SDC3 SHC1 SREBF2 TGM1 TRIP6 VIM YES1 YWHAB YWHAQ
Entrez ID		254950	3691
HPRD ID		11204	00946
Ensembl ID		ENSG00000186970	ENSG00000132470
Uniprot IDs		Q3LI76	A0A024R8K7 A0A024R8N2 A0A024R8T0 B7ZLD8 P16144
PDB IDs			1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A 4Q58 4WTW 4WTX 6GVK 6GVL
Enriched GO Terms of Interacting Partners?
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