APPL2 and PINK1

  • Data Source:
  • BioGRID (two hybrid)

APPL2

PINK1

Description adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 PTEN induced kinase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Proportion of activated microglia (inferior temporal cortex) ( 30679421)
Interacting Genes 29 interacting genes: APPL1 ATF3 CNMD CRADD CRBN CRLF3 DOK3 EPM2AIP1 KIFC3 KMT2C LDHAL6B LGALS9C LINC02875 LIX1 MLST8 MTA2 PINK1 POT1 PRR35 RAB22A RAB5A RAB5C RAI2 RBBP7 RBP7 RUVBL2 SUV39H2 TINF2 TSC1 16 interacting genes: APPL2 BAG2 BAG5 CRLS1 DNM1L FBXO7 HSH2D MAP3K7 MARK2 NEAT1 PARK7 SNCAIP STAT3 TGM2 TRAF6 UBE2M
Entrez ID 55198 65018
HPRD ID 06945 10514
Ensembl ID ENSG00000136044 ENSG00000158828
Uniprot IDs Q8NEU8 Q9BXM7
PDB IDs 4H8S 5C5B
Enriched GO Terms of Interacting Partners?
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