RPP25 and RPP38

Data Source:
HPRD (in vitro)

		RPP25	RPP38
Description		ribonuclease P and MRP subunit p25	ribonuclease P/MRP subunit p38
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex Centriolar Satellite	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		22 interacting genes: ABI2 BACH2 BANP DDI1 HOMEZ KRT15 LDOC1 LRRC73 PDLIM7 PICK1 PNMA1 POP1 POP4 POP5 POP7 RBPMS RPP14 RPP38 SAT1 SF3B4 TERF2IP ZNF438	9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40
Entrez ID		54913	10557
HPRD ID		15276	09360
Ensembl ID		ENSG00000178718	ENSG00000152464
Uniprot IDs		Q9BUL9	P78345
PDB IDs		6AHR 6AHU 6CWX	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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