RPP38 and RPP21

Data Source:
HPRD (two hybrid)

		RPP38	RPP21
Description		ribonuclease P/MRP subunit p38	ribonuclease P/MRP subunit p21
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GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease P Activity Ribonuclease P RNA Binding Metal Ion Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	TRNA 5'-leader Removal TRNA Processing Response To Drug RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Moderate to vigorous physical activity levels ( 29899525) Neurociticism ( 29500382) Neuroticism ( 29255261) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848)
Interacting Genes		9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40	3 interacting genes: RPP30 RPP38 RPP40
Entrez ID		10557	79897
HPRD ID		09360	15275
Ensembl ID		ENSG00000152464	ENSG00000241370
Uniprot IDs		P78345	A0A1U9X8H3 Q9H633
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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