RPP38 and RPP40

Data Source:
HPRD (in vivo)

		RPP38	RPP40
Description		ribonuclease P/MRP subunit p38	ribonuclease P/MRP subunit p40
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GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Ribonuclease MRP Activity Ribonuclease P Activity Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA 5'-leader Removal Endonucleolytic Cleavage Involved In TRNA Processing
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40	8 interacting genes: MEOX2 POP1 POP7 PTEN RPP14 RPP21 RPP30 RPP38
Entrez ID		10557	10799
HPRD ID		09360	09361
Ensembl ID		ENSG00000152464	ENSG00000124787
Uniprot IDs		P78345	A0A087X1N3 O75818
PDB IDs		6AHR 6AHU	6AHR 6AHU 6AHV
Enriched GO Terms of Interacting Partners?
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