BCOR and PCGF3

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		BCOR	PCGF3
Description		BCL6 corepressor	polycomb group ring finger 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm BCOR Complex	X Chromosome Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K36 Methylation Blastocyst Hatching Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization	Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Inactivation Of X Chromosome By Genetic Imprinting
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)	General cognitive ability ( 29844566) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemostatic factors and hematological phenotypes ( 22443383) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30297969 32499647) White blood cell count ( 32888494 27863252)
Interacting Genes		17 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF1 PCGF3 SP1 UBTD1 USP7	15 interacting genes: BCOR BCORL1 BMI1 CBX6 DZIP3 HNRNPK PHC1 PHC2 RING1 RNF2 TRIM55 TRIM63 TRIM9 UBE2C UBE2D3
Entrez ID		54880	10336
HPRD ID		06458	11515
Ensembl ID		ENSG00000183337	ENSG00000185619
Uniprot IDs		Q6W2J9	B3KQ06 B3KWT8 B4DTN5 Q3KNV8
PDB IDs		2N1L 3BIM 4HPL 6B7G
Enriched GO Terms of Interacting Partners?
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