UNC93A and CCL4

Data Source:
BioGRID (two hybrid)

		UNC93A	CCL4
Description		unc-93 homolog A	C-C motif chemokine ligand 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Molecular_function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding
	Biological Process	Biological_process	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Initial alcohol sensitivity ( 30276832) Urinary metabolite levels in chronic kidney disease ( 31959995)	Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		22 interacting genes: ABHD16A AQP6 ATP13A1 CCL4 CD300C CDIPT FCER1G FXYD6-FXYD2 GJA8 GPR101 GPR151 LNPEP PSCA RHAG SLC35E4 SLC39A7 SLC48A1 SYNGR1 TIMMDC1 TMEM14B TMEM237 TMX2	26 interacting genes: ACKR2 ARL13B CCL3 CCR1 CCR3 CCR5 CCR8 CNR2 CXCL8 GJA8 GPR152 GPRC5D MARCHF2 MRM1 SLC10A6 SLC18A1 SLC30A2 SLC30A8 SLC7A1 TAS2R5 TIMMDC1 TMEM14B TMEM179B TMEM31 TMEM86B UNC93A
Entrez ID		54346	6351
HPRD ID		12148	01657
Ensembl ID		ENSG00000112494	ENSG00000275302
Uniprot IDs		Q86WB7	P13236
PDB IDs			1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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