CCL4 and GPR152

Data Source:
BioGRID (two hybrid)

		CCL4	GPR152
Description		C-C motif chemokine ligand 4	G protein-coupled receptor 152
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding	G Protein-coupled Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis	G Protein-coupled Receptor Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Non-response to citalopram or escitalopram and depression ( 27622933) Refractive error ( 32231278)
Interacting Genes		26 interacting genes: ACKR2 ARL13B CCL3 CCR1 CCR3 CCR5 CCR8 CNR2 CXCL8 GJA8 GPR152 GPRC5D MARCHF2 MRM1 SLC10A6 SLC18A1 SLC30A2 SLC30A8 SLC7A1 TAS2R5 TIMMDC1 TMEM14B TMEM179B TMEM31 TMEM86B UNC93A	194 interacting genes: - ABCG4 ABHD16A ACSF2 ADIPOQ AGTRAP AIG1 ANKRD46 APOL3 AQP10 AQP3 AQP6 ARL6IP1 ARV1 ATP6V0C B3GNT7 BDNF BET1 BMP10 BNIP2 BNIP3 C14orf180 C1QL4 C8A CCDC167 CCL4 CCL4L2 CD53 CD72 CD81 CDIPT CDS2 CGRRF1 CLDND2 CLEC17A CLEC1A CLN5 CNIH1 COL8A2 COMT CRISP3 CSGALNACT2 CTXN3 CYB561 CYB561A3 CYB5B CYB5R3 CYBC1 DEFB108B DGAT2L6 EBP EDDM3B EFNA5 EMD ERG28 FA2H FAM20B FAXDC2 FDFT1 FUNDC2 FXYD3 FXYD6-FXYD2 GAST GJB2 GOLT1A GOLT1B GOSR2 GPR151 GPR37L1 HHATL HMOX1 HMOX2 IFNA8 IGF2 IGFBP5 IL1RL1 INS-IGF2 INSIG2 JAGN1 KCNA1 KCNN4 LAMB1 LAT LEPROTL1 LHFPL2 LHFPL5 LTC4S MAL MAL2 MFF MFSD5 MFSD6 MGLL MGST3 MMD MOSPD3 MS4A13 MYADML2 NAT8 NDUFB11 NEU1 NINJ2 NIPAL4 ORMDL1 ORMDL3 PEDS1-UBE2V1 PEX16 PGAP2 PIGF PIN1 PLN PNLIPRP1 PRAF2 PROM2 PTPRN RABAC1 RBFA REEP6 ROBO2 RTN3 RTP2 SACM1L SCAMP4 SCD SEC22B SERF1A SERF1B SERP2 SFT2D2 SFTPC SLC10A1 SLC13A4 SLC29A2 SLC30A3 SLC35A4 SLC35B1 SLC35B4 SLC35C2 SLC35F6 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC66A1 SLC66A2 SLC7A1 SMCO4 STATH STX1B STX3 STX4 STX5 STX8 SYT15 TAP1 TEX264 TFRC THSD7B TIMMDC1 TM4SF19 TMEM100 TMEM120B TMEM128 TMEM140 TMEM14B TMEM14C TMEM201 TMEM208 TMEM218 TMEM236 TMEM237 TMEM243 TMEM254 TMEM42 TMEM50B TMEM54 TMEM60 TMEM97 TMPPE TNFRSF10C TSNARE1 TSPAN33 TSPAN7 TSPO2 UBIAD1 UNC50 VAMP1 VAMP4 VAMP5 VKORC1 YIPF1 YIPF4 YIPF6 ZDHHC15
Entrez ID		6351	390212
HPRD ID		01657	13599
Ensembl ID		ENSG00000275302	ENSG00000175514
Uniprot IDs		P13236	A0A0I9RJ67 Q8TDT2
PDB IDs		1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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