CCL4 and TAS2R5

Data Source:
BioGRID (two hybrid)

		CCL4	TAS2R5
Description		C-C motif chemokine ligand 4	taste 2 receptor member 5
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity
	Biological Process	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Eosinophil Chemotaxis Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste G Protein-coupled Receptor Signaling Pathway Chemosensory Behavior
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Anorexia nervosa ( 23568457) Late-onset Alzheimer's disease ( 27770636)
Interacting Genes		26 interacting genes: ACKR2 ARL13B CCL3 CCR1 CCR3 CCR5 CCR8 CNR2 CXCL8 GJA8 GPR152 GPRC5D MARCHF2 MRM1 SLC10A6 SLC18A1 SLC30A2 SLC30A8 SLC7A1 TAS2R5 TIMMDC1 TMEM14B TMEM179B TMEM31 TMEM86B UNC93A	6 interacting genes: CCL4 RTP2 SFT2D2 SLC30A2 TMEM187 VAMP5
Entrez ID		6351	54429
HPRD ID		01657	05453
Ensembl ID		ENSG00000275302	ENSG00000127366
Uniprot IDs		P13236	A4D1U0 Q502V5 Q9NYW4
PDB IDs		1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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