POLD2 and POLDIP3

Data Source:
HPRD (two hybrid)

		POLD2	POLDIP3
Description		DNA polymerase delta 2, accessory subunit	DNA polymerase delta interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Zeta DNA Polymerase Complex DNA Polymerase Complex Delta DNA Polymerase Complex	Nucleoplasm Cytoplasm Cytosol Nuclear Speck Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding Protein Binding	RNA Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Telomere Maintenance DNA Replication DNA Strand Elongation Involved In DNA Replication Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Mismatch Repair Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication Nucleotide-excision Repair, DNA Incision DNA Damage Response, Detection Of DNA Damage DNA Biosynthetic Process	RNA Export From Nucleus MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing Positive Regulation Of Translation
Pathways		Recognition of DNA damage by PCNA-containing replication complex Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Removal of the Flap Intermediate from the C-strand Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: CCHCR1 CDK2 CDKN1A EP300 ERBB2 KCTD13 LSM6 PCNA POLD1 POLD3 POLD4 POLDIP2 POLDIP3 POLH SOX12 WRN WRNIP1 XRN1	28 interacting genes: BANP BICD2 CCNDBP1 ERH EXOSC8 GOLGA2 GTPBP3 HMBOX1 HOMEZ HSF2BP KRT31 KRT40 LZTS2 MID2 MTUS2 OSGIN1 OTX2 PIBF1 PNMA1 POLD2 POLR1C RAD51D RPS6KA1 RPS6KB1 SBK3 SRPK2 TEKT4 ZRANB1
Entrez ID		5425	84271
HPRD ID		15982	17875
Ensembl ID		ENSG00000106628	ENSG00000100227
Uniprot IDs		A0A087WWF6 P49005	B4E0L0 F6VRR5 Q659C6 Q9BY77
PDB IDs		3E0J 6S1M 6S1N 6S1O 6TNY 6TNZ
Enriched GO Terms of Interacting Partners?
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