PITPNA and NEO1

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		PITPNA	NEO1
Description		phosphatidylinositol transfer protein alpha	neogenin 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleoplasm Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Plasma Membrane Protein Complex
	Molecular Function	Protein Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylcholine Binding Phosphatidylinositol Binding Phosphatidylcholine Transfer Activity Phosphatidylglycerol Binding	Protein Binding Signaling Receptor Activity Co-receptor Binding
	Biological Process	Lipid Metabolic Process Visual Perception Phospholipid Transport Interleukin-12-mediated Signaling Pathway Intermembrane Lipid Transfer	Cell Adhesion Axon Guidance Positive Regulation Of BMP Signaling Pathway Iron Ion Homeostasis
Pathways		Role of second messengers in netrin-1 signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Netrin-1 signaling Myogenesis
Drugs		1,2-diacyl-sn-glycero-3-phosphoinositol (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
Diseases
GWAS		Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Adventurousness ( 30643258) Blood protein levels ( 30072576 29875488) Brain morphology (MOSTest) ( 32665545) Dentures ( 31235808) Face memory ( 31596458) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Red cell distribution width ( 32888494) Resting heart rate ( 27798624) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: CSNK2B DCC EGFR NEO1 PI4KA PIK3C3 PLCG1 SCP2	6 interacting genes: MTDH NTN1 NTN3 PITPNA PTK2 TTN
Entrez ID		5306	4756
HPRD ID		02548	03549
Ensembl ID		ENSG00000174238	ENSG00000067141
Uniprot IDs		Q00169 V9HWC5	Q59FP8 Q92859
PDB IDs		1UW5	1X5F 1X5G 1X5H 1X5I 1X5J 1X5K 3P4L
Enriched GO Terms of Interacting Partners?
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