PIN4 and FBL

Data Source:
HPRD (in vitro)

		PIN4	FBL
Description		peptidylprolyl cis/trans isomerase, NIMA-interacting 4	fibrillarin
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Mitochondrial Matrix Spindle	Fibrillar Center Dense Fibrillar Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D RNP Complex Small-subunit Processome Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization RRNA Processing	Box C/D RNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Rosacea symptom severity ( 29771307)
Interacting Genes		18 interacting genes: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAGEA11 PNMA1 SPTAN1 ZBTB9	22 interacting genes: DDX17 DDX5 ERG H2AC20 KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PRMT8 PSMB6 PTEN RUVBL1 RUVBL2 SIRT7 SMN1 SMN2 SNRPN TAF9 TBC1D17 ZNF792
Entrez ID		5303	2091
HPRD ID		02219	00617
Ensembl ID		ENSG00000102309	ENSG00000105202
Uniprot IDs		Q9Y237	P22087
PDB IDs		1EQ3 1FJD 3UI4 3UI5 3UI6	2IPX
Enriched GO Terms of Interacting Partners?
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