FBL and PIN4

Data Source:
HPRD (in vitro)

		FBL	PIN4
Description		fibrillarin	peptidylprolyl cis/trans isomerase, NIMA-interacting 4
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GO Annotations	Cellular Component	Fibrillar Center Dense Fibrillar Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D RNP Complex Small-subunit Processome Extracellular Exosome	Nucleoplasm Chromosome Nucleolus Mitochondrial Matrix Spindle
	Molecular Function	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity	DNA Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding
	Biological Process	Box C/D RNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation	Protein Peptidyl-prolyl Isomerization RRNA Processing
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Rosacea symptom severity ( 29771307)
Interacting Genes		22 interacting genes: DDX17 DDX5 ERG H2AC20 KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PRMT8 PSMB6 PTEN RUVBL1 RUVBL2 SIRT7 SMN1 SMN2 SNRPN TAF9 TBC1D17 ZNF792	18 interacting genes: ASCC2 CEP72 CSNK2A1 CSNK2A2 DNM1 EGFR ERBB2 ERBB3 ERBB4 EZH2 FAM9B FATE1 FBL FRMD1 MAGEA11 PNMA1 SPTAN1 ZBTB9
Entrez ID		2091	5303
HPRD ID		00617	02219
Ensembl ID		ENSG00000105202	ENSG00000102309
Uniprot IDs		P22087	Q9Y237
PDB IDs		2IPX	1EQ3 1FJD 3UI4 3UI5 3UI6
Enriched GO Terms of Interacting Partners?
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