PFDN5 and VBP1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PFDN5	VBP1
Description		prefoldin subunit 5	VHL binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton	Nucleus Cytoplasm Cytosol Polysome Prefoldin Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Amyloid-beta Binding Transcription Corepressor Activity Protein Binding Unfolded Protein Binding	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Amyloid Fibril Formation	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Interacting Genes		114 interacting genes: ABI2 ANKRD55 BCAS2 BCL6 BHLHE40 BRMS1 C10orf55 C10orf62 C20orf85 C22orf39 C4orf45 C7orf31 CALCOCO2 CCDC198 CSPP1 DMRT3 DOK4 DOK5 ELK3 ESPNL FAAP20 FAM102A FAM110A FAM214B FAM221A FAM222B FAM90A1 GLRX3 GLYCTK GPANK1 GSTO2 GUCD1 HAPLN2 HHEX HOXB9 HOXC8 IKBKG IKZF3 IL16 INCA1 IRX2 IRX6 ITSN1 KCTD9 KDM1A KLHL38 KLHL42 LARP4 LNX1 MAP2K5 METTL21A MISP MRPL45 MYC MYOT MYOZ1 NEUROG2 NOXA1 NTAQ1 PATZ1 PAX9 PFDN2 PFDN6 PHF1 PHF24 PILRA PITX1 PITX2 POGZ PPP1R32 PRKAB2 PRPF18 PRR35 PSMB4 PSMB8 PSME3 RIBC1 RIPPLY1 RSRC2 RUSC1 SAXO1 SCNM1 SDCBP SHISA6 SLAIN1 SMAP1 SMG9 SNAI1 SNRNP25 SNRPB SOHLH1 SPAG8 SPG21 STK19 SYCE1L SYT17 TAF6L TBX3 TCF19 TFG TLE5 TP73 TRAPPC6A TRIM28 TUBA1B TUBA3C VAX2 VBP1 VEZF1 VGLL1 WDR25 YPEL5 ZC2HC1C ZNF148	31 interacting genes: C1orf109 DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PFDN4 PFDN5 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576
Entrez ID		5204	7411
HPRD ID		05359	02135
Ensembl ID		ENSG00000123349	ENSG00000155959
Uniprot IDs		Q99471	D3DWY7 P61758 Q6FH24
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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