PFDN5 and FAM90A1

Data Source:
BioGRID (two hybrid)

		PFDN5	FAM90A1
Description		prefoldin subunit 5	family with sequence similarity 90 member A1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Prefoldin Complex Intermediate Filament Cytoskeleton
	Molecular Function	Amyloid-beta Binding Transcription Corepressor Activity Protein Binding Unfolded Protein Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Gut microbiota (functional units) ( 27694959)
Interacting Genes		114 interacting genes: ABI2 ANKRD55 BCAS2 BCL6 BHLHE40 BRMS1 C10orf55 C10orf62 C20orf85 C22orf39 C4orf45 C7orf31 CALCOCO2 CCDC198 CSPP1 DMRT3 DOK4 DOK5 ELK3 ESPNL FAAP20 FAM102A FAM110A FAM214B FAM221A FAM222B FAM90A1 GLRX3 GLYCTK GPANK1 GSTO2 GUCD1 HAPLN2 HHEX HOXB9 HOXC8 IKBKG IKZF3 IL16 INCA1 IRX2 IRX6 ITSN1 KCTD9 KDM1A KLHL38 KLHL42 LARP4 LNX1 MAP2K5 METTL21A MISP MRPL45 MYC MYOT MYOZ1 NEUROG2 NOXA1 NTAQ1 PATZ1 PAX9 PFDN2 PFDN6 PHF1 PHF24 PILRA PITX1 PITX2 POGZ PPP1R32 PRKAB2 PRPF18 PRR35 PSMB4 PSMB8 PSME3 RIBC1 RIPPLY1 RSRC2 RUSC1 SAXO1 SCNM1 SDCBP SHISA6 SLAIN1 SMAP1 SMG9 SNAI1 SNRNP25 SNRPB SOHLH1 SPAG8 SPG21 STK19 SYCE1L SYT17 TAF6L TBX3 TCF19 TFG TLE5 TP73 TRAPPC6A TRIM28 TUBA1B TUBA3C VAX2 VBP1 VEZF1 VGLL1 WDR25 YPEL5 ZC2HC1C ZNF148	162 interacting genes: ABI2 ACTN3 AKAP9 AMOTL2 ANKRD23 ANKRD29 AP2M1 APP ARHGEF9 ARRDC3 BANP BCAR1 BEGAIN BHLHB9 BLZF1 CADPS CALCOCO2 CARD9 CCDC13 CCDC57 CCN3 CCNC CCNL2 CDR2 CEP55 CEP70 CEP72 CEP76 CHRDL2 COG6 CYSRT1 DTX3 DVL2 DVL3 EFEMP2 ENKD1 EXOSC8 FAM228A FHL3 FLACC1 FLOT1 FOSB FSD2 FXR1 FXR2 FYN GABPB1 GCSAML GNPTAB GOLGA2 GOPC GPSM1 GRIPAP1 HAND2 HMBOX1 HOMER3 HOMEZ HOOK2 HSF2BP ISY1 KANK2 KASH5 KIFC3 KLHL12 KPNA3 KPNA6 KRT31 KRT34 KRT38 KRT40 KRTAP1-1 KRTAP10-8 LDOC1 LHX6 LIMS1 LMO2 LNX1 LRP2BP LRRK2 LZTS1 LZTS2 MAD1L1 MDFI MEIS3 MID2 MIPOL1 MLH1 MORN3 MSS51 MTUS2 MYOG NBPF19 NDUFB7 NOTCH2NLA NUDT21 OVOL1 PBX1 PBX2 PDLIM7 PFDN5 PICK1 PIH1D1 PLAGL2 POF1B PPARA PPP1R13B PRDM6 PRKAR1B PRR23B PSME3 PSTPIP1 RAB11FIP2 RABEP1 RBM48 REL RHOH RINT1 ROPN1 RPRD1A SH2B2 SIAH1 SMAD3 SMARCB1 SNW1 SPRED1 SRPK2 STAC3 STMN2 STX11 TAX1BP1 TEPSIN TFIP11 TLE5 TMCC2 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM42 TRIM54 TRIM55 TRIM69 TRIM9 TRIML2 VRTN VWC2 ZBTB14 ZBTB16 ZBTB7B ZBTB8A ZC2HC1C ZMYND12 ZNF143 ZNF212 ZNF343 ZNF526 ZNF581 ZNF655 ZNF688 ZNF76 ZWINT
Entrez ID		5204	55138
HPRD ID		05359	07672
Ensembl ID		ENSG00000123349	ENSG00000171847
Uniprot IDs		Q99471	Q86YD7
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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