VBP1 and PFDN4

Data Source:
BioGRID (biochemical, two hybrid)

		VBP1	PFDN4
Description		VHL binding protein 1	prefoldin subunit 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Prefoldin Complex Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Mitochondrion Cytosol Prefoldin Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding	Amyloid-beta Binding Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Atopic dermatitis ( 23042114) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Creatinine levels ( 31015462) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Obesity-related traits ( 23251661)
Interacting Genes		31 interacting genes: C1orf109 DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PFDN4 PFDN5 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576	7 interacting genes: ACTB ERBB3 PFDN2 RFPL3 TUBA4A TUBB VBP1
Entrez ID		7411	5203
HPRD ID		02135	05358
Ensembl ID		ENSG00000155959	ENSG00000101132
Uniprot IDs		D3DWY7 P61758 Q6FH24	Q9NQP4
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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