PFDN1 and KIAA0408

Data Source:
BioGRID (two hybrid)

		PFDN1	KIAA0408
Description		prefoldin subunit 1	KIAA0408
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	Asthma ( 31959851) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	42 interacting genes: ABI1 ABI3 AP2B1 BEGAIN CARD9 CBY2 CCDC57 CCDC85B CEP72 DCTN1 DTNBP1 FRS3 GFAP GRB2 HOOK2 HSF2BP KDM1A KRT15 MAGEA11 MDFI MYO15B NCK2 NDOR1 PFDN1 PHF1 PIK3R3 POLR3C PRMT6 RUNX1T1 SFN SORBS3 TEX11 TLE1 TRAF2 TRIM37 TRIM55 TRIM63 UBASH3A VIM XRCC6 YWHAG ZDHHC17
Entrez ID		5201	9729
HPRD ID		05357	17187
Ensembl ID		ENSG00000113068	ENSG00000189367
Uniprot IDs		O60925	Q6ZU52
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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