PFDN1 and CCDC85A

Data Source:
BioGRID (two hybrid)

		PFDN1	CCDC85A
Description		prefoldin subunit 1	coiled-coil domain containing 85A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Prefoldin Complex	Adherens Junction
	Molecular Function	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding
	Biological Process	Protein Folding Negative Regulation Of Amyloid Fibril Formation	Biological_process
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Copper levels ( 26025379) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Menarche (age at onset) ( 21102462 25231870) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Type 2 diabetes ( 26818947)
Interacting Genes		54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	5 interacting genes: NEK2 PFDN1 STMN2 SYTL5 TP53BP2
Entrez ID		5201	114800
HPRD ID		05357	19098
Ensembl ID		ENSG00000113068	ENSG00000055813
Uniprot IDs		O60925	Q96PX6
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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