PALS2 and PTF1A

Data Source:
BioGRID (affinity chromatography technology)

		PALS2	PTF1A
Description		protein associated with LIN7 2, MAGUK family member	pancreas associated transcription factor 1a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Exosome	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein-containing Complex Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development
Pathways			Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases			Permanent neonatal diabetes mellitus (PNDM)
GWAS			Type 2 diabetes ( 32499647)
Interacting Genes		30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1	11 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10
Entrez ID		51678	256297
HPRD ID		09509	09526
Ensembl ID		ENSG00000105926	ENSG00000168267
Uniprot IDs		A0A024RA25 B8ZZG1 Q9NZW5	Q7RTS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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