PTF1A and CCDC27

Data Source:
BioGRID (two hybrid)

		PTF1A	CCDC27
Description		pancreas associated transcription factor 1a	coiled-coil domain containing 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Developmental Process Amacrine Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development
Pathways		Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases		Permanent neonatal diabetes mellitus (PNDM)
GWAS		Type 2 diabetes ( 32499647)	Blood trace element (Cu levels) ( 23720494) Hematocrit ( 32888494) Hemoglobin concentration ( 27863252) Obesity-related traits ( 23251661) Red cell distribution width ( 28957414) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Visceral fat ( 22589738)
Interacting Genes		11 interacting genes: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	2 interacting genes: MAGEA11 PTF1A
Entrez ID		256297	148870
HPRD ID		09526	08141
Ensembl ID		ENSG00000168267	ENSG00000162592
Uniprot IDs		Q7RTS3	Q2M243
PDB IDs
Enriched GO Terms of Interacting Partners?
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