MPC1 and ACTC1

Data Source:
HPRD (two hybrid)

		MPC1	ACTC1
Description		mitochondrial pyruvate carrier 1	actin alpha cardiac muscle 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Mitochondrial Inner Membrane	Extracellular Space Cytoplasm Cytosol Dynactin Complex Actin Filament Focal Adhesion Membrane Sarcomere Lamellipodium Filopodium I Band Cell Body Extracellular Exosome Blood Microparticle
	Molecular Function	Molecular_function Protein Binding Pyruvate Transmembrane Transporter Activity	ATP Binding ATPase Activity Myosin Binding
	Biological Process	Mitochondrial Pyruvate Transmembrane Transport Biological_process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Drug Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration
Pathways		Pyruvate metabolism	Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS			Axial length ( 24144296) Refractive error ( 32231278 20835239)
Interacting Genes		4 interacting genes: ACTC1 GABARAP MAGED1 MPC2	41 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG ASH2L BCL11A C1QTNF9 CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1
Entrez ID		51660	70
HPRD ID		07091	00015
Ensembl ID		ENSG00000060762	ENSG00000159251
Uniprot IDs		Q5TI65 Q9Y5U8	B3KPP5 P68032
PDB IDs
Enriched GO Terms of Interacting Partners?
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