ACTC1 and ABLIM3

Data Source:
HPRD (in vivo, in vitro)

		ACTC1	ABLIM3
Description		actin alpha cardiac muscle 1	actin binding LIM protein family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Actin Filament Focal Adhesion Membrane Sarcomere Lamellipodium Filopodium I Band Cell Body Extracellular Exosome Blood Microparticle	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium Glutamatergic Synapse
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	Protein Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Drug Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Transcription, DNA-templated Lamellipodium Assembly Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Striated Muscle Contraction	DCC mediated attractive signaling
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Axial length ( 24144296) Refractive error ( 32231278 20835239)	Body mass index ( 25673413) Chronic obstructive pulmonary disease ( 30804561) Diastolic blood pressure ( 26390057 28739976) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) FEV1 ( 30804560) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Macular thickness ( 30535121) Peak expiratory flow ( 30804560)
Interacting Genes		41 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG ASH2L BCL11A C1QTNF9 CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	15 interacting genes: ABI2 ACTC1 BANP BRCA1 CATSPER1 CBX8 CCDC33 CWF19L2 HIKESHI IKZF3 PALMD SNW1 SSX2IP TFIP11 ZNF620
Entrez ID		70	22885
HPRD ID		00015	12411
Ensembl ID		ENSG00000159251	ENSG00000173210
Uniprot IDs		B3KPP5 P68032	A0A0C4DGA7 O94929
PDB IDs			1UJS 2DJ7
Enriched GO Terms of Interacting Partners?
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