UBE2J1 and PJA2

Data Source:
BioGRID (two hybrid)

		UBE2J1	PJA2
Description		ubiquitin conjugating enzyme E2 J1	praja ring finger ubiquitin ligase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Spermatid Development Protein N-linked Glycosylation Via Asparagine Ubiquitin-dependent ERAD Pathway Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Inflammatory Response Long-term Memory Regulation Of Protein Kinase A Signaling Protein Ubiquitination Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Hippo Signaling Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of JNK Cascade Positive Regulation Of P38MAPK Cascade
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Body mass index ( 29273807) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549)
Interacting Genes		48 interacting genes: AQP2 BIRC2 BRCA1 CD79A CDS1 CLTRN CREB3 CYB561 DERL1 DIO2 EBP ELOVL4 FAM209A FAM210B FCER1G GKN1 GOLT1A JAGN1 LAPTM5 LRSAM1 LY6G6C LYVE1 MAPKAPK2 MFSD14B MFSD3 MS4A6E PJA2 PLPPR2 PRKN PROKR2 REEP4 RNF2 SEC11C SLC10A6 SLC26A5 TLCD4 TM4SF18 TM4SF19 TMEM14B TMEM31 TMEM51 TMX2 TOPORS TRHR TRIM27 TRIM63 UBA1 UBC	14 interacting genes: KSR1 MAGED1 MFHAS1 MOB1A PRKAR1A PRKAR2A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W
Entrez ID		51465	9867
HPRD ID		15599	11436
Ensembl ID		ENSG00000198833	ENSG00000198961
Uniprot IDs		Q9Y385	O43164
PDB IDs
Enriched GO Terms of Interacting Partners?
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