SNX9 and PI4KA

Data Source:
BioGRID (pull down)

		SNX9	PI4KA
Description		sorting nexin 9	phosphatidylinositol 4-kinase alpha
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GO Annotations	Cellular Component	Ruffle Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Cuticular Plate Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Viral Replication Complex Golgi-associated Vesicle Membrane Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Ubiquitin Protein Ligase Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Arp2/3 Complex Binding	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Cadherin Binding Phosphatidylinositol Kinase Activity
	Biological Process	Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Receptor-mediated Endocytosis Endosomal Transport Positive Regulation Of Actin Filament Polymerization Cleavage Furrow Formation Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Membrane Protein Ectodomain Proteolysis Lipid Tube Assembly Membrane Organization Protein-containing Complex Assembly Plasma Membrane Tubulation	Phosphatidylinositol Biosynthetic Process Signal Transduction Phosphorylation Viral RNA Genome Replication Multi-organism Membrane Organization Viral Replication Complex Formation And Maintenance Phosphatidylinositol Phosphorylation Phosphatidylinositol-mediated Signaling
Pathways		Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis	Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Heart rate response to beta blockers ( 29478026) Lipoprotein (a) - cholesterol levels ( 25575512) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252)	Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)
Interacting Genes		23 interacting genes: ADAM15 ADAM9 AP1G1 CLTC DAPK1 DNM1 DNM2 EGFR FASLG ITCH KHDRBS1 LRRK1 MPHOSPH6 PAK2 PALS2 PI4KA PIK3CA PIK3R5 SOS1 SOS2 TNK2 WAS WASL	10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1
Entrez ID		51429	5297
HPRD ID		12072	08972
Ensembl ID		ENSG00000130340	ENSG00000241973
Uniprot IDs		Q9Y5X1	B4DYG5 P42356 Q4LE69
PDB IDs		2RAI 2RAJ 2RAK 3DYT 3DYU 3LGE	6BQ1
Enriched GO Terms of Interacting Partners?
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